Testosterone is a hormone that plays a significant role in a man’s life. It is not only linked to sex drive but also affects energy, mood, muscle strength, bone health, and even memory. As men get older, their testosterone levels naturally go down each year. Research shows that total testosterone can fall by about 0.4% each year from the mid-30s, while the free testosterone that the body can use drops even faster, at around 1.3% per year.
When testosterone levels get lower, men may start to notice changes in daily life. This can include feeling tired more often, losing strength, having less interest in sex, or finding it more challenging to stay positive and motivated. Studies using medical questionnaires show that the most common problems linked to low testosterone are low energy, weaker physical ability, poor memory, and reduced sexual health. Men with the lowest levels of testosterone often notice the most considerable improvements when they receive treatment.
In this blog, we will look at how testosterone affects men’s bodies and minds, the signs of low testosterone, the possible benefits and risks of testosterone replacement therapy (TRT), and practical lifestyle steps that can help. The goal is to give clear and valuable information that helps men make better choices for their long-term health and well-being.
Testosterone is often called the “male hormone”, but it is essential to know that women also have it, just in much smaller amounts. In men, testosterone is made mainly in the testicles and is controlled by the brain through signals sent by the pituitary gland.
This hormone has many jobs in the body. It helps to:
As men get older, testosterone levels naturally begin to drop. Most men will see a slow decrease starting around the age of 30 to 40. Research suggests that total testosterone levels fall by around 0.4% each year, and free testosterone (the type the body can use easily) falls by about 1.3% each year. This gradual decline is sometimes called age-related hypogonadism or androgen deficiency of the ageing male.
For many men, this drop is so slow that it causes few noticeable changes. But for others, the fall in testosterone can lead to a range of physical, mental, and emotional symptoms that reduce quality of life. Understanding this natural decline is the first step in recognising when low testosterone may be affecting health and wellbeing.
Testosterone is the primary male sex hormone, produced mainly in the testes and smaller amounts by the adrenal glands. It plays a key role in turning boys into men by developing secondary sex characteristics such as a deeper voice, facial hair, and increased muscle mass.
Although women also make testosterone, their levels are about 15 times lower than men’s.
To perform these functions properly, the body needs enough testosterone. When levels drop, many of these processes are disrupted. This can affect not only physical health, such as bone and muscle strength, weight control, and sexual function, but also mental performance, mood, and overall quality of life.
When testosterone gets too low, it can change the way men feel and live each day. These changes can affect the body, the mind, and even relationships. Here are the main areas where low testosterone has the most significant impact.
Low testosterone can make men lose muscle and strength, so everyday tasks feel harder. Bones can also become weaker, which means a higher chance of breaks and injuries. Men with low testosterone are more likely to gain fat around the belly and may have a greater risk of health problems like diabetes or anaemia (not enough red blood cells) (study).
Testosterone is also linked to mood. When levels are low, men may feel sad, worried, less confident, or less interested in activities they once enjoyed. It can also be harder to stay focused or motivated. Research shows that low testosterone can make depression worse, and depression can also lower testosterone.
Many men with low testosterone notice changes in their sex life. This can mean less interest in sex, weaker erections, or less pleasure during intimacy. These changes can sometimes affect confidence and relationships, too.
Here is a simple table to show how low testosterone affects different parts of life:
Area of Life |
What Can Happen |
Body Health |
Muscle loss, weaker bones, belly fat, and diabetes risk |
Mood and Feelings |
Sadness, anxiety, poor focus, and less motivation |
Sex and Intimacy |
Low sex drive, erection problems, and less satisfaction |
Energy |
Feeling tired, less drive to stay active |
Researchers have found that testosterone levels slowly drop as men get older. Unlike women, who experience a sudden fall in oestrogen during menopause, men go through a gradual decline. This happens because the brain sends weaker signals to the testes, leading to lower testosterone production over time.
Low testosterone is not just linked to ageing. It can also occur at any age due to health conditions such as type 2 diabetes, HIV, obesity, or even some cancers. Since testosterone plays a role in energy, behaviour, mood, and confidence, its shortage can affect many parts of a man’s life.
The table below shows the main areas of health that can be affected:
Health Area |
Effect of Low Testosterone |
Physical Strength |
Loss of muscle, reduced stamina, and overall weakness |
Sexual Function |
Lower sex drive, difficulty with erections |
Cognitive Function |
Poor memory, lack of focus, “brain fog” |
Emotional Health |
Depression, anxiety, irritability, low motivation |
Bone Health |
Weaker bones, higher risk of fractures |
Sleep |
Insomnia, restless nights, daytime tiredness |
Metabolism |
Weight gain, especially around the stomach |
Confidence & Appearance |
Hair thinning, lower self-esteem, reduced drive |
Testosterone is vital for building and keeping muscle. When levels drop, men can lose muscle size and find it harder to maintain strength. Although some studies suggest muscle function may not be affected as much as muscle volume, the change in body shape can make men feel weaker, appear thinner, and lower their confidence.
Many men with low testosterone say they feel tired even after a good night’s sleep. Energy levels fall, making it harder to stay active at work, exercise regularly, or enjoy family time. This constant tiredness can reduce productivity and affect overall quality of life.
As the primary male sex hormone, testosterone plays a key role in desire and performance. Low levels can lead to reduced sex drive, weaker erections, and a lower volume of semen. These issues often affect intimacy and can put strain on relationships.
Low testosterone can affect brain function, making it harder to focus, remember details, or stay mentally sharp. While memory decline is common with ageing, studies suggest testosterone deficiency adds to the problem. Some research shows that testosterone therapy may improve specific cognitive skills in older men.
Testosterone supports bone growth and strength. When levels are low, bones lose density, increasing the risk of fractures as men age. This is one of the reasons older men with low testosterone are more prone to osteoporosis.
Low testosterone can disturb sleep. Men may notice lighter, shorter sleep, higher levels of cortisol (the stress hormone), and increased daytime tiredness. Sleep apnoea is also more common in men with low testosterone, leading to broken sleep and further fatigue.
Testosterone helps the body use fat for energy. Without enough of it, fat builds up, especially around the stomach. This not only affects appearance and self-esteem but also raises the risk of heart disease and type 2 diabetes.
Low testosterone often affects emotions. Men may feel sad, anxious, or less interested in social activities. Studies show they are more likely to develop depression and anxiety compared with men who have healthy testosterone levels.
Testosterone also helps to stabilise mood. Low levels can make men more irritable and quick-tempered, causing everyday situations to feel more stressful.
The mix of low energy, reduced muscle, weight gain, weaker sexual performance, and mood changes can all damage self-confidence. Hair thinning or loss, another effect of low testosterone, can further affect appearance and self-esteem.
If you think you have symptoms of low testosterone, the first step is to get your levels checked with a blood test. This is a simple test that can be arranged by your GP or a specialist. A small sample of blood is taken from your arm and sent to a laboratory for analysis.
There are two primary forms of testosterone in the blood:
When the results come back, doctors usually look at both total testosterone (the sum of free and bound testosterone) and, in some cases, free testosterone, especially if total levels are borderline.
Testosterone levels naturally rise and fall during the day. They are highest in the early morning and lowest in the evening. For this reason, the test is usually done between 7 am and 10 am to get the most accurate reading.
In healthy men, total testosterone levels are usually between 300 and 1,000 nanograms per decilitre (ng/dL), which is about 10 to 35 nanomoles per litre (nmol/L) in UK measurements (study). Levels below 300 ng/dL (10 nmol/L) may indicate low testosterone. To confirm a diagnosis, doctors often recommend two or three separate tests on different mornings, as levels can change from day to day.
Testosterone replacement therapy (TRT) is one of the most common treatments for men with low testosterone. It works by restoring hormone levels to a healthier range, which can ease symptoms and improve overall well-being.
TRT can be given in several forms, including injections, skin gels, patches, creams, or small implants placed under the skin. Your doctor will choose the correct method and dose based on your test results, age, and health needs.
Many men report noticeable benefits after starting TRT. These may include:
TRT Method |
How It Works |
Pros |
Considerations |
Injections |
Testosterone is injected into the muscle every 1–4 weeks |
Long-lasting, effective, usually affordable |
Hormone levels may rise and fall between doses |
Gels/Creams |
Applied daily to the skin and absorbed into the blood |
Easy to use, steady hormone release |
Risk of transfer to others through skin contact |
Patches |
Worn on the skin, releasing testosterone gradually |
Convenient, steady levels |
May cause skin irritation, needs daily use |
Pellets/Implants |
Small pellets are inserted under the skin every 3–6 months |
Long-lasting, no daily action required |
Minor surgical procedure, not easily adjusted |
Since every man responds differently, TRT should constantly be monitored by a healthcare professional to make sure the treatment is both safe and effective. If you think low testosterone may be affecting your quality of life, speaking to your doctor about TRT could be an essential step forward.
Testosterone is the primary male sex hormone that supports muscle strength, bone density, red blood cell production, sex drive, and emotional well-being. Healthy testosterone levels are essential for maintaining energy, mood, and overall quality of life in men.
Testosterone levels in men usually start to decline gradually from around the age of 30 to 40. This natural decrease in testosterone can affect energy, strength, mood, and sex drive, which is why many men notice symptoms of low testosterone as they grow older.
Low testosterone symptoms include fatigue, reduced muscle mass, weight gain around the stomach, low sex drive, weaker erections, poor focus, memory issues, mood swings, and hair loss. These low testosterone signs can vary from mild to severe depending on age and health.
Doctors usually check testosterone levels with a simple morning blood test, measuring both total testosterone and free testosterone. To confirm a low testosterone diagnosis, most physicians recommend at least two or three separate tests on different mornings.
Testosterone replacement therapy, also called TRT, is a medical treatment that restores hormone levels in men with low testosterone. It can be given through injections, gels, patches, or implants, helping to improve sex drive, mood, muscle mass, bone strength, and energy.
TRT can improve quality of life for men by increasing energy, building muscle mass, improving bone density, boosting sex drive, enhancing mood, supporting better slee,p and reducing symptoms of depression caused by low testosterone.
Yes, TRT may have side effects such as acne, oily skin, mood changes, sleep apnoea, infertility, and an increased red blood cell count. Some studies also suggest a possible link between testosterone therapy and cardiovascular risks, so medical monitoring is essential.
Yes, lifestyle changes such as regular exercise, strength training, healthy eating with enough healthy fats, better sleep, and reducing stress can naturally support testosterone production. Weight loss in overweight men is also proven to help increase testosterone levels.
Testosterone is essential for a man's physical and mental health. Low testosterone levels can lead to decreased self-confidence, reduced energy, decreased muscle mass, weakened bone strength, and impaired cognitive abilities.
You should get treatment to keep your testosterone levels healthy. Testosterone replacement therapy is an excellent option to boost testosterone levels effectively. It can counteract the consequences of low testosterone and enhance your mental, emotional, and physical health. If you want to increase your testosterone levels and are considering testosterone replacement therapy, we can help. Contact us for expert guidance and personalised treatment options.